Monday, July 27, 2009

Stepwise EGFR-HER2 activation & phosphorylation

Stepwise EGFR-HER2 activation and phosphorylation - link

EGFR-HER2 receptor complex is an important trigger of the oncogenic process. The process of tyrosine phosphorylation upon receptor activation undergoes a sequence of molecular steps that ultimately lead to signal transduction in cancer.


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